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Discovery of novel alkylated (bis)urea and (bis)thiourea polyamine analogues with potent antimalarial activities
A series of alkylated (bis)urea and (bis)thiourea polyamine analogues were synthesized and screened for antimalarial activity against chloroquine-sensitive and -resistant strains of Plasmodium falciparum in vitro. All analogues showed growth inhibitory activity against P. falciparum at less than 3 μ...
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| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3191323/ https://ncbi.nlm.nih.gov/pubmed/21882831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm200463z |
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