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Discovery of novel alkylated (bis)urea and (bis)thiourea polyamine analogues with potent antimalarial activities
A series of alkylated (bis)urea and (bis)thiourea polyamine analogues were synthesized and screened for antimalarial activity against chloroquine-sensitive and -resistant strains of Plasmodium falciparum in vitro. All analogues showed growth inhibitory activity against P. falciparum at less than 3 μ...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3191323/ https://ncbi.nlm.nih.gov/pubmed/21882831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm200463z |
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