Combined hyperlipidemia in transgenic mice overexpressing human apolipoprotein Cl.

We have generated transgenic mice over-expressing human apolipoprotein CI (apo CI) using the native gene joined to the downstream 154-bp liver-specific enhancer that we defined for apo E. Human apo CI (HuCI)-transgenic mice showed elevation of plasma triglycerides (mg/dl) compared to controls in bot...

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Autors principals: Shachter, N S, Ebara, T, Ramakrishnan, R, Steiner, G, Breslow, J L, Ginsberg, H N, Smith, J D
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC507495/
https://ncbi.nlm.nih.gov/pubmed/8698877
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