Combined hyperlipidemia in transgenic mice overexpressing human apolipoprotein Cl.

We have generated transgenic mice over-expressing human apolipoprotein CI (apo CI) using the native gene joined to the downstream 154-bp liver-specific enhancer that we defined for apo E. Human apo CI (HuCI)-transgenic mice showed elevation of plasma triglycerides (mg/dl) compared to controls in bot...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Shachter, N S, Ebara, T, Ramakrishnan, R, Steiner, G, Breslow, J L, Ginsberg, H N, Smith, J D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507495/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8698877/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118857
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