Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E-deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma.

Many reactive products may be formed when LDL undergoes lipid peroxidation, which in turn can react with lipids, apoproteins, and proteins, generating immunogenic neoepitopes. Autoantibodies recognizing model epitopes of oxidized low density lipoprotein, such as malondialdehydelysine, occur in plasm...

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Pubblicato in:	J Clin Invest
Autori principali:	Palinski, W, Hörkkö, S, Miller, E, Steinbrecher, U P, Powell, H C, Curtiss, L K, Witztum, J L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507491/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8698873/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118853
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