Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid–protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins

We recently cloned monoclonal IgM autoantibodies which bind to epitopes of oxidized low-density lipoprotein (OxLDL) from apoE-deficient mice (EO(–) autoantibodies). We now demonstrate that those EO(–) autoantibodies that were originally selected for binding to copper-oxidized low-density lipoprotein...

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Main Authors: Hörkkö, Sohvi, Bird, David A., Miller, Elizabeth, Itabe, Hiroyuki, Leitinger, Norbert, Subbanagounder, Ganesamoorthy, Berliner, Judith A., Friedman, Peter, Dennis, Edward A., Curtiss, Linda K., Palinski, Wulf, Witztum, Joseph L.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC407862/
https://ncbi.nlm.nih.gov/pubmed/9884341
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