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Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E-deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma.

Many reactive products may be formed when LDL undergoes lipid peroxidation, which in turn can react with lipids, apoproteins, and proteins, generating immunogenic neoepitopes. Autoantibodies recognizing model epitopes of oxidized low density lipoprotein, such as malondialdehydelysine, occur in plasm...

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Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Palinski, W, Hörkkö, S, Miller, E, Steinbrecher, U P, Powell, H C, Curtiss, L K, Witztum, J L
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1996
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507491/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8698873/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118853
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