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The epitopes for some antiphospholipid antibodies are adducts of oxidized phospholipid and β(2 )glycoprotein 1 (and other proteins)

Circulating autoantibodies to phospholipids (aPLs), such as cardiolipin (CL), are found in patients with antiphospholipid antibody syndrome (APS). We recently demonstrated that many aPLs bound to CL only after it had been oxidized (OxCL), but not to a reduced CL analogue that could not undergo oxida...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Hörkkö, Sohvi, Miller, Elizabeth, Branch, D. Ware, Palinski, Wulf, Witztum, Joseph L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23367/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9294215/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.19.10356
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