Metabolic Labeling with an Alkyne-modified Isoprenoid Analog Facilitates Imaging and Quantification of the Prenylome in Cells

[Image: see text] Protein prenylation is a post-translational modification that is responsible for membrane association and protein–protein interactions. The oncogenic protein Ras, which is prenylated, has been the subject of intense study in the past 20 years as a therapeutic target. Several studie...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ACS Chem Biol
Prif Awduron: Palsuledesai, Charuta C., Ochocki, Joshua D., Kuhns, Michelle M., Wang, Yen-Chih, Warmka, Janel K., Chernick, Dustin S., Wattenberg, Elizabeth V., Li, Ling, Arriaga, Edgar A., Distefano, Mark D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2016
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074897/
https://ncbi.nlm.nih.gov/pubmed/27525511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00421
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