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A combination of metabolic labeling and 2D-DIGE analysis in response to a farnesyltransferase inhibitor facilitates the discovery of new prenylated proteins

Protein prenylation is a post-translational modification required for proper cellular localization and activity of many important eukaryotic proteins. Farnesyltransferase inhibitors (FTIs) have been explored extensively for their antitumor activity. To assist in identifying potentially new and more...

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Detalhes bibliográficos
Main Authors: Palsuledesai, Charuta C., Ochocki, Joshua D., Markowski, Todd W., Distefano, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058996/
https://ncbi.nlm.nih.gov/pubmed/24577581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3mb70593e
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