Combined systemic elimination of MET and EGFR signaling completely abolishes liver regeneration and leads to liver decompensation

Receptor tyrosine kinases MET and EGFR are critically involved in initiation of liver regeneration. Other cytokines and signaling molecules also participate in the early part of the process. Regeneration employs effective redundancy schemes to compensate for the missing signals. Elimination of any s...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Hepatology
Päätekijät: Paranjpe, Shirish, Bowen, William C., Mars, Wendy M., Orr, Anne, Haynes, Meagan M., DeFrances, Marie C., Liu, Silvia, Tseng, George C., Tsagianni, Anastasia, Michalopoulos, George K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074871/
https://ncbi.nlm.nih.gov/pubmed/27397846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28721
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