Basic fibroblast growth factor induces matrix metalloproteinase-13 via ERK MAP kinase-altered phosphorylation and sumoylation of Elk-1 in human adult articular chondrocytes

Degradation of the extracellular matrix (ECM) by matrix metalloproteinases (MMPs) and release of basic fibroblast growth factor (bFGF) are principal aspects of the pathology of osteoarthritis (OA). ECM disruption leads to bFGF release, which activates the extracellular signal-regulated kinase/mitoge...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Open Access Rheumatol
Main Authors: Im, Hee-Jeong, Sharrocks, Andrew D, Lin, Xia, Yan, Dongyao, Kim, Jaesung, van Wijnen, Andre J, Hipskind, Robert A
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2009
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074718/
https://ncbi.nlm.nih.gov/pubmed/27789988
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados