A suppressive effect of prostaglandin E(2) on the expression of SERPINE1/plasminogen activator inhibitor-1 in human articular chondrocytes: An in vitro pilot study

Prostaglandin E(2) (PGE(2)) is expressed in articular joints with inflammatory arthropathy and may exert catabolic effects leading to cartilage degradation. As we observed in a preliminary experiment that PGE(2) suppressed the expression of SERPINE1/plasminogen activator inhibitor (PAI)-1 mRNA in ch...

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Publicado en:Open Access Rheumatol
Autores principales: Masuko, Kayo, Murata, Minako, Suematsu, Naoya, Okamoto, Kazuki, Yudoh, Kazuo, Shimizu, Hiroyuki, Beppu, Moroe, Nakamura, Hiroshi, Kato, Tomohiro
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2009
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074716/
https://ncbi.nlm.nih.gov/pubmed/27789978
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