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Sphingosine-1-phosphate attenuates proteoglycan aggrecan expression via production of prostaglandin E<sub>2 </sub>from human articular chondrocytes
<p>Abstract</p> <p>Background</p> <p>Sphingosine-1-phosphate (S1P), a downstream metabolite of ceramide, induces various bioactivities via two distinct pathways: as an intracellular second messenger or through receptor activation. The receptor for S1P (S1PR) is the fami...
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| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2007-03-01
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| Colecção: | BMC Musculoskeletal Disorders |
| Acesso em linha: | http://www.biomedcentral.com/1471-2474/8/29 |
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