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Prostaglandin E(2 )regulates the expression of connective tissue growth factor (CTGF/CCN2) in human osteoarthritic chondrocytes via the EP4 receptor

BACKGROUND: The regulatory mechanisms of the expression of connective tissue growth factor/CCN family member 2 (CTGF/CCN2) in human articular chondrocytes have not been clarified. We investigated the effect of prostaglandin E(2 )(PGE(2)) on CTGF/CCN2 expression in chondrocytes. FINDINGS: Articular c...

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Detalhes bibliográficos
Main Authors: Masuko, Kayo, Murata, Minako, Yudoh, Kazuo, Shimizu, Hiroyuki, Beppu, Moroe, Nakamura, Hiroshi, Kato, Tomohiro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826353/
https://ncbi.nlm.nih.gov/pubmed/20205862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-3-5
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