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Nonalcoholic Steatohepatitis Modulates Membrane Protein Retrieval and Insertion Processes

Interindividual variability in drug response in nonalcoholic steatohepatitis (NASH) can be mediated by altered regulation of drug metabolizing enzymes and transporters. Among these is the mislocalization of multidrug resistance-associated protein (MRP2)/Mrp2 away from the canalicular membrane, which...

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Bibliografiske detaljer
Udgivet i:Drug Metab Dispos
Main Authors: Dzierlenga, A. L., Clarke, J. D., Cherrington, N. J.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074469/
https://ncbi.nlm.nih.gov/pubmed/27604106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.116.071415
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