Down‐regulation of TIMP2 by HIF‐1α/miR‐210/HIF‐3α regulatory feedback circuit enhances cancer metastasis in hepatocellular carcinoma

Cancer metastasis is a multistep process that involves a series of tumor‐stromal interaction, including extracellular matrix (ECM) remodeling, which requires a concerted action of multiple proteolytic enzymes and their endogenous inhibitors. This study investigated the role of tissue inhibitor of me...

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Bibliographic Details
Published in:Hepatology
Main Authors: Kai, Alan Ka‐Lun, Chan, Lo Kong, Lo, Regina Cheuk‐Lam, Lee, Joyce Man‐Fong, Wong, Carmen Chak‐Lui, Wong, Jack Chun‐Ming, Ng, Irene Oi‐Lin
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Hepatobiliary Malignancies
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074303/
https://ncbi.nlm.nih.gov/pubmed/27018975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28577
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