A positive feedback loop promotes HIF‐1α stability through miR‐210‐mediated suppression of RUNX3 in paraquat‐induced EMT

Irreversible pulmonary fibrosis induced by paraquat (PQ) poisoning is the major cause of death in patients with PQ poisoning. The epithelial–mesenchymal transition (EMT) is postulated to be one of the main mechanisms of pulmonary fibrosis. Here, we investigated the role of miR‐210 in PQ‐induced EMT...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Mol Med
Prif Awduron: Zhu, Yong, Wang, Jinfeng, Meng, Xiaoxiao, Xie, Hui, Tan, Jiuting, Guo, Xinkun, Han, Peng, Wang, Ruilan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2017
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706527/
https://ncbi.nlm.nih.gov/pubmed/28699703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13264
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