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Co-regulation of mRNA translation by TDP-43 and Fragile X Syndrome protein FMRP

For proper mammalian brain development and functioning, the translation of many neuronal mRNAs needs to be repressed without neuronal activity stimulations. We have discovered that the expression of a subclass of neuronal proteins essential for neurodevelopment and neuron plasticity is co-regulated...

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Библиографические подробности
Опубликовано в: :Acta Neuropathol
Главные авторы: Majumder, Pritha, Chu, Jen-Fei, Chatterjee, Biswanath, Swamy, Krishna B. S., Shen, Che-Kun James
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Berlin Heidelberg 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073124/
https://ncbi.nlm.nih.gov/pubmed/27518042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-016-1603-8
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