A Novel Diphenylthiosemicarbazide Is a Potential Insulin Secretagogue for Anti-Diabetic Agent

Insulin secretagogues are used for treatment of type 2 diabetes. We attempted to discover novel small molecules to stimulate insulin secretion by using in silico similarity search using sulfonylureas as query, followed by measurement of insulin secretion. Among 38 compounds selected by in silico sim...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sugawara, Kenji, Honda, Kohei, Reien, Yoshie, Yokoi, Norihide, Seki, Chihiro, Takahashi, Harumi, Minami, Kohtaro, Mori, Ichiro, Matsumoto, Akio, Nakaya, Haruaki, Seino, Susumu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072725/
https://ncbi.nlm.nih.gov/pubmed/27764176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164785
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