Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.

We tested the hypothesis that angiotensin II-induced hypertension is associated with an increase in vascular .O2- production, and characterized the oxidase involved in this process. Infusion of angiotensin II (0.7 mg/kg per d) increased systolic blood pressure and doubled vascular .O2- production (a...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Rajagopalan, S, Kurz, S, Münzel, T, Tarpey, M, Freeman, B A, Griendling, K K, Harrison, D G
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1996
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507261/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8621776/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118623
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares