Transcription of the tumor necrosis factor alpha gene is rapidly induced by anti-immunoglobulin and blocked by cyclosporin A and FK506 in human B cells.

The human tumor necrosis factor alpha (TNF-alpha) gene encodes a cytokine whose activities have been implicated in many immunopathological processes, including the activation and differentiation of lymphocytes. Originally identified as a monocyte factor, our studies and those of others have demonstr...

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Main Authors: Goldfeld, A E, Flemington, E K, Boussiotis, V A, Theodos, C M, Titus, R G, Strominger, J L, Speck, S H
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC50726/
https://ncbi.nlm.nih.gov/pubmed/1281550
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