Effects of cyclosporin A and FK506 on Fc epsilon receptor type I-initiated increases in cytokine mRNA in mouse bone marrow-derived progenitor mast cells: resistance to FK506 is associated with a deficiency in FK506-binding protein FKBP12.

The inhibitory effects of cyclosporin A (CsA) and FK506 on Fc epsilon receptor type I-initiated increases in cytokine mRNA and the expression of their intracellular binding proteins were studied in interleukin 3 (IL-3)-dependent, mouse bone marrow-derived mast cells (BMMCs). In BMMCs sensitized with...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Kaye, R E, Fruman, D A, Bierer, B E, Albers, M W, Zydowsky, L D, Ho, S I, Jin, Y J, Castells, M C, Schreiber, S L, Walsh, C T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49956/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1382293/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.18.8542
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