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Stimulation of Nipah Fusion: Small Intradomain Changes Trigger Extensive Interdomain Rearrangements

Nipah is an emerging paramyxovirus that is of serious concern to human health. It invades host cells using two of its membrane proteins—G and F. G binds to host ephrins and this stimulates G to activate F. Upon activation, F mediates virus-host membrane fusion. Here we focus on mechanisms that under...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Dutta, Priyanka, Siddiqui, Ahnaf, Botlani, Mohsen, Varma, Sameer
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071607/
https://ncbi.nlm.nih.gov/pubmed/27760350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.09.002
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