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Large interdomain rearrangement triggered by suppression of micro- to millisecond dynamics in bacterial Enzyme I
Enzyme I (EI), the first component of the bacterial phosphotransfer signal transduction system, undergoes one of the largest substrate-induced interdomain rearrangements documented to date. Here, we characterize the perturbations generated by two small molecules, the natural substrate phosphoenolpyr...
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| Published in: | Nat Commun |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4293084/ https://ncbi.nlm.nih.gov/pubmed/25581904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6960 |
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