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Stimulation of Nipah Fusion: Small Intradomain Changes Trigger Extensive Interdomain Rearrangements

Nipah is an emerging paramyxovirus that is of serious concern to human health. It invades host cells using two of its membrane proteins—G and F. G binds to host ephrins and this stimulates G to activate F. Upon activation, F mediates virus-host membrane fusion. Here we focus on mechanisms that under...

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Dettagli Bibliografici
Pubblicato in:Biophys J
Autori principali: Dutta, Priyanka, Siddiqui, Ahnaf, Botlani, Mohsen, Varma, Sameer
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071607/
https://ncbi.nlm.nih.gov/pubmed/27760350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.09.002
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