Generation and characterization of urokinase receptor-deficient mice.

Mice homozygously deficient for the urokinase-type plasminogen activator (u-PA) receptor (u-PAR-1-) were generated by homologous recombination in D3, embryonic stem cells. The genomic sequences comprising exon 2 through 5 of the u-PAR gene were replaced by the neomycin resistance gene, resulting in...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Dewerchin, M, Nuffelen, A V, Wallays, G, Bouché, A, Moons, L, Carmeliet, P, Mulligan, R C, Collen, D
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507128/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8609247/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118489
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