Generation and characterization of urokinase receptor-deficient mice.

Mice homozygously deficient for the urokinase-type plasminogen activator (u-PA) receptor (u-PAR-1-) were generated by homologous recombination in D3, embryonic stem cells. The genomic sequences comprising exon 2 through 5 of the u-PAR gene were replaced by the neomycin resistance gene, resulting in...

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Autores principales: Dewerchin, M, Nuffelen, A V, Wallays, G, Bouché, A, Moons, L, Carmeliet, P, Mulligan, R C, Collen, D
Formato: Artigo
Lenguaje:Inglês
Publicado: 1996
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC507128/
https://ncbi.nlm.nih.gov/pubmed/8609247
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