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Regulation of HIF-1α stability by lysine methylation
The level and activity of critical regulatory proteins in cells are tightly controlled by several tiers of post-translational modifications. HIF-1α is maintained at low levels under normoxia conditions by the collaboration between PHD proteins and the VHL-containing E3 ubiquitin ligase complex. We r...
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| Veröffentlicht in: | BMB Rep |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Korean Society for Biochemistry and Molecular Biology
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5070701/ https://ncbi.nlm.nih.gov/pubmed/26973343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2016.49.5.053 |
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