An injectable nanoparticle generator enhances delivery of cancer therapeutics

The efficacy of cancer drugs is often limited because only a small fraction of the administered dose accumulates in tumors. Here we report an injectable nanoparticle generator (iNPG) that overcomes multiple biological barriers to cancer drug delivery. The iNPG is a discoidal micrometer-sized particl...

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Gepubliceerd in:Nat Biotechnol
Hoofdauteurs: Xu, Rong, Zhang, Guodong, Mai, Junhua, Deng, Xiaoyong, Segura-Ibarra, Victor, Wu, Suhong, Shen, Jianliang, Liu, Haoran, Hu, Zhenhua, Chen, Lingxiao, Huang, Yi, Koay, Eugene, Huang, Yu, Liu, Jun, Ensor, Joe E., Blanco, Elvin, Liu, Xuewu, Ferrari, Mauro, Shen, Haifa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070674/
https://ncbi.nlm.nih.gov/pubmed/26974511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3506
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