Multistage Vectored siRNA Targeting Ataxia-Telangiectasia Mutated for Breast Cancer Therapy

The ataxia-telangiectasia mutated (ATM) protein plays a central role in DNA damage response and cell cycle checkpoints, and may be a promising target for cancer therapy if normal tissue toxicity could be avoided. Our strategy to target ATM for breast cancer therapy involves the use of liposomal-enca...

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Hlavní autoři: Xu, Rong, Huang, Yi, Mai, Junhua, Zhang, Guodong, Guo, Xiaojing, Xia, Xiaojun, Koay, Eugene J, Li, Qingpo, Liu, Xuewu, Ferrari, Mauro, Shen, Haifa
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842236/
https://ncbi.nlm.nih.gov/pubmed/23293085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201201510
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