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A chloroquine-induced macrophage-preconditioning strategy for improved nanodelivery

Site-specific localization is critical for improving the therapeutic efficacy and safety of drugs. Nanoparticles have emerged as promising tools for localized drug delivery. However, over 90% of systemically injected nanocarriers typically accumulate in the liver and spleen due to resident macrophag...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wolfram, Joy, Nizzero, Sara, Liu, Haoran, Li, Feng, Zhang, Guodong, Li, Zheng, Shen, Haifa, Blanco, Elvin, Ferrari, Mauro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653759/
https://ncbi.nlm.nih.gov/pubmed/29062065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14221-2
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