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Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages.

The presence of oxysterols in macrophages isolated from atherosclerotic tissue and the effect of oxysterols on the regulation of lipoprotein lipase (LPL) mRNA were studied. Both rabbit and human macrophages, freshly isolated from atherosclerotic aorta, show about the same distribution of oxysterols,...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Hultén, L M, Lindmark, H, Diczfalusy, U, Björkhem, I, Ottosson, M, Liu, Y, Bondjers, G, Wiklund, O
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507038/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8567968/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118436
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