Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages.

The presence of oxysterols in macrophages isolated from atherosclerotic tissue and the effect of oxysterols on the regulation of lipoprotein lipase (LPL) mRNA were studied. Both rabbit and human macrophages, freshly isolated from atherosclerotic aorta, show about the same distribution of oxysterols,...

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Publicado en:	J Clin Invest
Autores principales:	Hultén, L M, Lindmark, H, Diczfalusy, U, Björkhem, I, Ottosson, M, Liu, Y, Bondjers, G, Wiklund, O
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Clinical Investigation 1996
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507038/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8567968/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118436
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