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Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages.

The presence of oxysterols in macrophages isolated from atherosclerotic tissue and the effect of oxysterols on the regulation of lipoprotein lipase (LPL) mRNA were studied. Both rabbit and human macrophages, freshly isolated from atherosclerotic aorta, show about the same distribution of oxysterols,...

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Опубликовано в::J Clin Invest
Главные авторы: Hultén, L M, Lindmark, H, Diczfalusy, U, Björkhem, I, Ottosson, M, Liu, Y, Bondjers, G, Wiklund, O
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1996
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507038/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8567968/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118436
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