Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages.

The presence of oxysterols in macrophages isolated from atherosclerotic tissue and the effect of oxysterols on the regulation of lipoprotein lipase (LPL) mRNA were studied. Both rabbit and human macrophages, freshly isolated from atherosclerotic aorta, show about the same distribution of oxysterols,...

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Main Authors: Hultén, L M, Lindmark, H, Diczfalusy, U, Björkhem, I, Ottosson, M, Liu, Y, Bondjers, G, Wiklund, O
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC507038/
https://ncbi.nlm.nih.gov/pubmed/8567968
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