Effects of early-life exposure to THIP on phenotype development in a mouse model of Rett syndrome

BACKGROUND: Rett syndrome (RTT) is a neurodevelopmental disorder caused mostly by disruptions in the MECP2 gene. MECP2-null mice show imbalances in neuronal excitability and synaptic communications. Several previous studies indicate that augmenting synaptic GABA receptors (GABA(A)Rs) can alleviate R...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Neurodev Disord
Autors principals: Zhong, Weiwei, Johnson, Christopher Mychal, Wu, Yang, Cui, Ningren, Xing, Hao, Zhang, Shuang, Jiang, Chun
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069883/
https://ncbi.nlm.nih.gov/pubmed/27777634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11689-016-9169-2
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars