Effects of early-life exposure to THIP on phenotype development in a mouse model of Rett syndrome

BACKGROUND: Rett syndrome (RTT) is a neurodevelopmental disorder caused mostly by disruptions in the MECP2 gene. MECP2-null mice show imbalances in neuronal excitability and synaptic communications. Several previous studies indicate that augmenting synaptic GABA receptors (GABA(A)Rs) can alleviate R...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurodev Disord
Main Authors: Zhong, Weiwei, Johnson, Christopher Mychal, Wu, Yang, Cui, Ningren, Xing, Hao, Zhang, Shuang, Jiang, Chun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069883/
https://ncbi.nlm.nih.gov/pubmed/27777634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11689-016-9169-2
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados