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Defects in brainstem neurons associated with breathing and motor function in the Mecp2(R168X/Y) mouse model of Rett syndrome

Rett Syndrome (RTT) is an X-linked neurodevelopmental disorder caused mostly by disruption of the MECP2 gene. Among several RTT-like mouse models, one of them is a strain of mice that carries an R168X point mutation in Mecp2 and resembles one of the most common RTT-causing mutations in humans. Altho...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Johnson, Christopher M., Zhong, Weiwei, Cui, Ningren, Wu, Yang, Xing, Hao, Zhang, Shuang, Jiang, Chun
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206293/
https://ncbi.nlm.nih.gov/pubmed/27653984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00132.2016
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