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Mecp2 disruption in rats causes reshaping in firing activity and patterns of brainstem respiratory neurons

People with Rett Syndrome (RTT), a neurodevelopmental disorder caused by mutations in the MECP2 gene, have breathing abnormalities manifested as periodical hypoventilation with compensatory hyperventilation, which are attributable to a high incidence of sudden death. Similar breathing abnormalities...

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Détails bibliographiques
Publié dans:Neuroscience
Auteurs principaux: Wu, Yang, Cui, Ningren, Xing, Hao, Zhong, Weiwei, Arrowood, Colin, Johnson, Christopher M., Jiang, Chun
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415544/
https://ncbi.nlm.nih.gov/pubmed/30458221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2018.11.011
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