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Effects of early‐life exposure to THIP on brainstem neuronal excitability in the Mecp2‐null mouse model of Rett syndrome before and after drug withdrawal

Rett syndrome (RTT) is mostly caused by mutations of the X‐linked MECP2 gene. Although the causal neuronal mechanisms are still unclear, accumulating experimental evidence obtained from Mecp2 (−/Y) mice suggests that imbalanced excitation/inhibition in central neurons plays a major role. Several app...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Zhong, Weiwei, Johnson, Christopher M., Cui, Ningren, Oginsky, Max F., Wu, Yang, Jiang, Chun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5269412/
https://ncbi.nlm.nih.gov/pubmed/28108647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13110
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