Hyperresponse to T-Cell Receptor Signaling and Apoptosis of Id1 Transgenic Thymocytes
The basic helix-loop-helix transcription factors, E2A and HEB, play important roles in T-cell development at multiple checkpoints. Expression of their inhibitor, Id1, abolishes the function of both transcription factors in a dose-dependent manner. The Id1 transgenic thymus is characterized by an acc...
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| Publicado en: | Mol Cell Biol |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC506975/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15314144/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.17.7313-7323.2004 |
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