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Hyperresponse to T-Cell Receptor Signaling and Apoptosis of Id1 Transgenic Thymocytes

The basic helix-loop-helix transcription factors, E2A and HEB, play important roles in T-cell development at multiple checkpoints. Expression of their inhibitor, Id1, abolishes the function of both transcription factors in a dose-dependent manner. The Id1 transgenic thymus is characterized by an acc...

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Detalhes bibliográficos
Main Authors: Qi, Zengbiao, Sun, Xiao-Hong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC506975/
https://ncbi.nlm.nih.gov/pubmed/15314144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7313-7323.2004
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