Protein Kinase Cα Activates c-Src and Induces Podosome Formation via AFAP-110

We report that the actin filament-associated protein AFAP-110 is required to mediate protein kinase Cα (PKCα) activation of the nonreceptor tyrosine kinase c-Src and the subsequent formation of podosomes. Immunofluorescence analysis demonstrated that activation of PKCα by phorbol 12-myristate 13-ace...

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Bibliografiska uppgifter
Huvudupphovsmän: Gatesman, Amanda, Walker, Valerie G., Baisden, Joseph M., Weed, Scott A., Flynn, Daniel C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2004
Ämnen:
Cell Growth and Development
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC506973/
https://ncbi.nlm.nih.gov/pubmed/15314167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7578-7597.2004
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