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Protein Kinase Cα Activates c-Src and Induces Podosome Formation via AFAP-110
We report that the actin filament-associated protein AFAP-110 is required to mediate protein kinase Cα (PKCα) activation of the nonreceptor tyrosine kinase c-Src and the subsequent formation of podosomes. Immunofluorescence analysis demonstrated that activation of PKCα by phorbol 12-myristate 13-ace...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC506973/ https://ncbi.nlm.nih.gov/pubmed/15314167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7578-7597.2004 |
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