LEDGF/p75 Determines Cellular Trafficking of Diverse Lentiviral but Not Murine Oncoretroviral Integrase Proteins and Is a Component of Functional Lentiviral Preintegration Complexes

Human immunodeficiency virus type 1 (HIV-1), feline immunodeficiency virus (FIV), and Moloney murine leukemia virus (MoMLV) integrases were stably expressed to determine their intracellular trafficking. Each lentiviral integrase localized to cell nuclei in close association with chromatin while the...

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Bibliographic Details
Main Authors: Llano, Manuel, Vanegas, Maria, Fregoso, Oliver, Saenz, Dyana, Chung, Susan, Peretz, Mary, Poeschla, Eric M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC506940/
https://ncbi.nlm.nih.gov/pubmed/15308744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.17.9524-9537.2004
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