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Integrase, LEDGF/p75 and HIV Replication

HIV integrates a DNA copy of its genome into a host cell chromosome in each replication cycle. The essential DNA cleaving and joining chemistry of integration is known, but there is less understanding of the process as it occurs in a cell, where two complex and dynamic macromolecular entities are jo...

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Dettagli Bibliografici
Autore principale: Poeschla, Eric M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902792/
https://ncbi.nlm.nih.gov/pubmed/18264802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-008-7540-5
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