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Integrase, LEDGF/p75 and HIV Replication
HIV integrates a DNA copy of its genome into a host cell chromosome in each replication cycle. The essential DNA cleaving and joining chemistry of integration is known, but there is less understanding of the process as it occurs in a cell, where two complex and dynamic macromolecular entities are jo...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3902792/ https://ncbi.nlm.nih.gov/pubmed/18264802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-008-7540-5 |
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