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Efficient Unified Rare Variant Association Test by Modeling the Population Genetic Distribution in Case-control Studies
Recent advancements in next-generation DNA sequencing technologies have made it plausible to study the association of rare variants with complex diseases. Due to the low frequency, rare variants need to be aggregated in association tests to achieve adequate power with reasonable sample sizes. Hierar...
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| Yayımlandı: | Genet Epidemiol |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5069155/ https://ncbi.nlm.nih.gov/pubmed/27550412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21995 |
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