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Utilizing Population Controls in Rare-Variant Case-Parent Association Tests
There is great interest in detecting associations between human traits and rare genetic variation. To address the low power implicit in single-locus tests of rare genetic variants, many rare-variant association approaches attempt to accumulate information across a gene, often by taking linear combin...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4121482/ https://ncbi.nlm.nih.gov/pubmed/24836453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2014.04.014 |
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