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A Permutation Procedure to Correct for Confounders in Case-Control Studies, Including Tests of Rare Variation

Many case-control tests of rare variation are implemented in statistical frameworks that make correction for confounders like population stratification difficult. Simple permutation of disease status is unacceptable for resolving this issue because the replicate data sets do not have the same confou...

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Main Authors: Epstein, Michael P., Duncan, Richard, Jiang, Yunxuan, Conneely, Karen N., Allen, Andrew S., Satten, Glen A.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415546/
https://ncbi.nlm.nih.gov/pubmed/22818855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.06.004
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