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Assessing the Impact of Population Stratification on Association Studies of Rare Variation

AIMS: The study of rare variants, which can potentially explain a great proportion of heritability, has emerged as an important topic in human gene mapping of complex diseases. Although several statistical methods have been developed to increase the power to detect disease-related rare variants, non...

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Bibliographic Details
Published in:Hum Hered
Main Authors: Jiang, Yunxuan, Epstein, Michael P., Conneely, Karen N.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406348/
https://ncbi.nlm.nih.gov/pubmed/23921847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000353270
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