Chargement en cours...
Testing Rare-Variant Association without Calling Genotypes Allows for Systematic Differences in Sequencing between Cases and Controls.
Next-generation sequencing of DNA provides an unprecedented opportunity to discover rare genetic variants associated with complex diseases and traits. However, the common practice of first calling underlying genotypes and then treating the called values as known is prone to false positive findings,...
Enregistré dans:
| Auteurs principaux: | , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science (PLoS)
2016-05-01
|
| Collection: | PLoS Genetics |
| Accès en ligne: | http://europepmc.org/articles/PMC4859496?pdf=render |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|